diff --git a/bench_test.go b/bench_test.go
index a4440bc1c..da78d65c8 100644
--- a/bench_test.go
+++ b/bench_test.go
@@ -163,6 +163,41 @@ func BenchmarkMinimalPgConnPreparedSelect(b *testing.B) {
 	}
 }
 
+func BenchmarkMinimalPgConnPreparedStatementDescriptionSelect(b *testing.B) {
+	conn := mustConnect(b, mustParseConfig(b, os.Getenv("PGX_TEST_DATABASE")))
+	defer closeConn(b, conn)
+
+	pgConn := conn.PgConn()
+
+	psd, err := pgConn.Prepare(context.Background(), "ps1", "select $1::int8", nil)
+	if err != nil {
+		b.Fatal(err)
+	}
+
+	encodedBytes := make([]byte, 8)
+
+	b.ResetTimer()
+	for i := 0; i < b.N; i++ {
+
+		rr := pgConn.ExecPreparedStatementDescription(context.Background(), psd, [][]byte{encodedBytes}, []int16{1}, []int16{1})
+		if err != nil {
+			b.Fatal(err)
+		}
+
+		for rr.NextRow() {
+			for i := range rr.Values() {
+				if !bytes.Equal(rr.Values()[0], encodedBytes) {
+					b.Fatalf("unexpected values: %s %s", rr.Values()[i], encodedBytes)
+				}
+			}
+		}
+		_, err = rr.Close()
+		if err != nil {
+			b.Fatal(err)
+		}
+	}
+}
+
 func BenchmarkPointerPointerWithNullValues(b *testing.B) {
 	conn := mustConnect(b, mustParseConfig(b, os.Getenv("PGX_TEST_DATABASE")))
 	defer closeConn(b, conn)
@@ -1282,6 +1317,51 @@ func BenchmarkSelectRowsPgConnExecPrepared(b *testing.B) {
 	}
 }
 
+func BenchmarkSelectRowsPgConnExecPreparedStatementDescription(b *testing.B) {
+	conn := mustConnectString(b, os.Getenv("PGX_TEST_DATABASE"))
+	defer closeConn(b, conn)
+
+	rowCounts := getSelectRowsCounts(b)
+
+	psd, err := conn.PgConn().Prepare(context.Background(), "ps1", "select n, 'Adam', 'Smith ' || n, 'male', '1952-06-16'::date, 258, 72, '{foo,bar,baz}'::text[], '2001-01-28 01:02:03-05'::timestamptz from generate_series(100001, 100000 + $1) n", nil)
+	if err != nil {
+		b.Fatal(err)
+	}
+
+	for _, rowCount := range rowCounts {
+		b.Run(fmt.Sprintf("%d rows", rowCount), func(b *testing.B) {
+			formats := []struct {
+				name string
+				code int16
+			}{
+				{"text", pgx.TextFormatCode},
+				{"binary - mostly", pgx.BinaryFormatCode},
+			}
+			for _, format := range formats {
+				b.Run(format.name, func(b *testing.B) {
+					for i := 0; i < b.N; i++ {
+						rr := conn.PgConn().ExecPreparedStatementDescription(
+							context.Background(),
+							psd,
+							[][]byte{[]byte(strconv.FormatInt(rowCount, 10))},
+							nil,
+							[]int16{format.code, pgx.TextFormatCode, pgx.TextFormatCode, pgx.TextFormatCode, format.code, format.code, format.code, format.code, format.code},
+						)
+						for rr.NextRow() {
+							rr.Values()
+						}
+
+						_, err := rr.Close()
+						if err != nil {
+							b.Fatal(err)
+						}
+					}
+				})
+			}
+		})
+	}
+}
+
 type queryRecorder struct {
 	conn      net.Conn
 	writeBuf  []byte
diff --git a/pgconn/pgconn.go b/pgconn/pgconn.go
index 5c77a836e..84133f292 100644
--- a/pgconn/pgconn.go
+++ b/pgconn/pgconn.go
@@ -22,6 +22,7 @@ import (
 	"github.com/jackc/pgx/v5/pgconn/ctxwatch"
 	"github.com/jackc/pgx/v5/pgconn/internal/bgreader"
 	"github.com/jackc/pgx/v5/pgproto3"
+	"github.com/jackc/pgx/v5/pgtype"
 )
 
 const (
@@ -1165,7 +1166,7 @@ func (pgConn *PgConn) ExecParams(ctx context.Context, sql string, paramValues []
 	pgConn.frontend.SendParse(&pgproto3.Parse{Query: sql, ParameterOIDs: paramOIDs})
 	pgConn.frontend.SendBind(&pgproto3.Bind{ParameterFormatCodes: paramFormats, Parameters: paramValues, ResultFormatCodes: resultFormats})
 
-	pgConn.execExtendedSuffix(result)
+	pgConn.execExtendedSuffix(result, nil, nil)
 
 	return result
 }
@@ -1190,7 +1191,37 @@ func (pgConn *PgConn) ExecPrepared(ctx context.Context, stmtName string, paramVa
 
 	pgConn.frontend.SendBind(&pgproto3.Bind{PreparedStatement: stmtName, ParameterFormatCodes: paramFormats, Parameters: paramValues, ResultFormatCodes: resultFormats})
 
-	pgConn.execExtendedSuffix(result)
+	pgConn.execExtendedSuffix(result, nil, nil)
+
+	return result
+}
+
+// ExecPreparedStatementDescription enqueues the execution of a prepared statement via the PostgreSQL extended query
+// protocol.
+//
+// This differs from ExecPrepared in that it takes a *StatementDescription instead of just the prepared statement name.
+// Because it has the *StatementDescription it can avoid the Describe Portal message that ExecPrepared must send to get
+// the result column descriptions.
+//
+// paramValues are the parameter values. It must be encoded in the format given by paramFormats.
+//
+// paramFormats is a slice of format codes determining for each paramValue column whether it is encoded in text or
+// binary format. If paramFormats is nil all params are text format. ExecPrepared will panic if len(paramFormats) is not
+// 0, 1, or len(paramValues).
+//
+// resultFormats is a slice of format codes determining for each result column whether it is encoded in text or binary
+// format. If resultFormats is nil all results will be in text format.
+//
+// ResultReader must be closed before PgConn can be used again.
+func (pgConn *PgConn) ExecPreparedStatementDescription(ctx context.Context, statementDescription *StatementDescription, paramValues [][]byte, paramFormats, resultFormats []int16) *ResultReader {
+	result := pgConn.execExtendedPrefix(ctx, paramValues)
+	if result.closed {
+		return result
+	}
+
+	pgConn.frontend.SendBind(&pgproto3.Bind{PreparedStatement: statementDescription.Name, ParameterFormatCodes: paramFormats, Parameters: paramValues, ResultFormatCodes: resultFormats})
+
+	pgConn.execExtendedSuffix(result, statementDescription, resultFormats)
 
 	return result
 }
@@ -1230,8 +1261,10 @@ func (pgConn *PgConn) execExtendedPrefix(ctx context.Context, paramValues [][]by
 	return result
 }
 
-func (pgConn *PgConn) execExtendedSuffix(result *ResultReader) {
-	pgConn.frontend.SendDescribe(&pgproto3.Describe{ObjectType: 'P'})
+func (pgConn *PgConn) execExtendedSuffix(result *ResultReader, statementDescription *StatementDescription, resultFormats []int16) {
+	if statementDescription == nil {
+		pgConn.frontend.SendDescribe(&pgproto3.Describe{ObjectType: 'P'})
+	}
 	pgConn.frontend.SendExecute(&pgproto3.Execute{})
 	pgConn.frontend.SendSync(&pgproto3.Sync{})
 
@@ -1245,7 +1278,7 @@ func (pgConn *PgConn) execExtendedSuffix(result *ResultReader) {
 		return
 	}
 
-	result.readUntilRowDescription()
+	result.readUntilRowDescription(statementDescription, resultFormats)
 }
 
 // CopyTo executes the copy command sql and copies the results to w.
@@ -1662,13 +1695,36 @@ func (rr *ResultReader) Close() (CommandTag, error) {
 
 // readUntilRowDescription ensures the ResultReader's fieldDescriptions are loaded. It does not return an error as any
 // error will be stored in the ResultReader.
-func (rr *ResultReader) readUntilRowDescription() {
+func (rr *ResultReader) readUntilRowDescription(statementDescription *StatementDescription, resultFormats []int16) {
 	for !rr.commandConcluded {
 		// Peek before receive to avoid consuming a DataRow if the result set does not include a RowDescription method.
 		// This should never happen under normal pgconn usage, but it is possible if SendBytes and ReceiveResults are
 		// manually used to construct a query that does not issue a describe statement.
 		msg, _ := rr.pgConn.peekMessage()
 		if _, ok := msg.(*pgproto3.DataRow); ok {
+			if statementDescription != nil {
+				rr.fieldDescriptions = statementDescription.Fields
+				// Adjust field descriptions for resultFormats
+				if len(resultFormats) == 0 {
+					// No format codes provided, default to text format
+					for i := range rr.fieldDescriptions {
+						rr.fieldDescriptions[i].Format = pgtype.TextFormatCode
+					}
+				} else if len(resultFormats) == 1 {
+					// Single format code applies to all columns
+					for i := range rr.fieldDescriptions {
+						rr.fieldDescriptions[i].Format = resultFormats[0]
+					}
+				} else if len(resultFormats) == len(rr.fieldDescriptions) {
+					// One format code per column
+					for i := range rr.fieldDescriptions {
+						rr.fieldDescriptions[i].Format = resultFormats[i]
+					}
+				} else {
+					// This should be impossible to reach as the mismatch would have been caught earlier.
+					rr.concludeCommand(CommandTag{}, fmt.Errorf("mismatched result format codes length"))
+				}
+			}
 			return
 		}
 
diff --git a/pgconn/pgconn_test.go b/pgconn/pgconn_test.go
index 3663bc904..e22f81c48 100644
--- a/pgconn/pgconn_test.go
+++ b/pgconn/pgconn_test.go
@@ -1439,6 +1439,146 @@ func TestConnExecPreparedEmptySQL(t *testing.T) {
 	ensureConnValid(t, pgConn)
 }
 
+func TestConnExecPreparedStatementDescription(t *testing.T) {
+	t.Parallel()
+
+	ctx, cancel := context.WithTimeout(context.Background(), 120*time.Second)
+	defer cancel()
+
+	pgConn, err := pgconn.Connect(ctx, os.Getenv("PGX_TEST_DATABASE"))
+	require.NoError(t, err)
+	defer closeConn(t, pgConn)
+
+	psd, err := pgConn.Prepare(ctx, "ps1", "select $1::text as msg", nil)
+	require.NoError(t, err)
+	require.NotNil(t, psd)
+	assert.Len(t, psd.ParamOIDs, 1)
+	assert.Len(t, psd.Fields, 1)
+
+	result := pgConn.ExecPreparedStatementDescription(ctx, psd, [][]byte{[]byte("Hello, world")}, nil, nil)
+	require.Len(t, result.FieldDescriptions(), 1)
+	assert.Equal(t, "msg", result.FieldDescriptions()[0].Name)
+
+	rowCount := 0
+	for result.NextRow() {
+		rowCount += 1
+		assert.Equal(t, "Hello, world", string(result.Values()[0]))
+	}
+	assert.Equal(t, 1, rowCount)
+	commandTag, err := result.Close()
+	assert.Equal(t, "SELECT 1", commandTag.String())
+	assert.NoError(t, err)
+
+	ensureConnValid(t, pgConn)
+}
+
+type byteCounterConn struct {
+	conn         net.Conn
+	bytesRead    int
+	bytesWritten int
+}
+
+func (cbn *byteCounterConn) Read(b []byte) (n int, err error) {
+	n, err = cbn.conn.Read(b)
+	cbn.bytesRead += n
+	return n, err
+}
+
+func (cbn *byteCounterConn) Write(b []byte) (n int, err error) {
+	n, err = cbn.conn.Write(b)
+	cbn.bytesWritten += n
+	return n, err
+}
+
+func (cbn *byteCounterConn) Close() error {
+	return cbn.conn.Close()
+}
+
+func (cbn *byteCounterConn) LocalAddr() net.Addr {
+	return cbn.conn.LocalAddr()
+}
+
+func (cbn *byteCounterConn) RemoteAddr() net.Addr {
+	return cbn.conn.RemoteAddr()
+}
+
+func (cbn *byteCounterConn) SetDeadline(t time.Time) error {
+	return cbn.conn.SetDeadline(t)
+}
+
+func (cbn *byteCounterConn) SetReadDeadline(t time.Time) error {
+	return cbn.conn.SetReadDeadline(t)
+}
+
+func (cbn *byteCounterConn) SetWriteDeadline(t time.Time) error {
+	return cbn.conn.SetWriteDeadline(t)
+}
+
+func TestConnExecPreparedStatementDescriptionNetworkUsage(t *testing.T) {
+	t.Parallel()
+
+	ctx, cancel := context.WithTimeout(context.Background(), 120*time.Second)
+	defer cancel()
+
+	config, err := pgconn.ParseConfig(os.Getenv("PGX_TEST_DATABASE"))
+	require.NoError(t, err)
+
+	var counterConn *byteCounterConn
+	config.AfterNetConnect = func(ctx context.Context, config *pgconn.Config, conn net.Conn) (net.Conn, error) {
+		counterConn = &byteCounterConn{conn: conn}
+		return counterConn, nil
+	}
+
+	pgConn, err := pgconn.ConnectConfig(ctx, config)
+	require.NoError(t, err)
+	defer closeConn(t, pgConn)
+	require.NotNil(t, counterConn)
+
+	if pgConn.ParameterStatus("crdb_version") != "" {
+		t.Skip("Server uses different number of bytes for same operations")
+	}
+
+	psd, err := pgConn.Prepare(ctx, "ps1", "select n, 'Adam', 'Smith ' || n, 'male', '1952-06-16'::date, 258, 72, '{foo,bar,baz}'::text[], '2001-01-28 01:02:03-05'::timestamptz from generate_series(100001, 100000 + $1) n", nil)
+	require.NoError(t, err)
+	require.NotNil(t, psd)
+	assert.Len(t, psd.ParamOIDs, 1)
+	assert.Len(t, psd.Fields, 9)
+
+	counterConn.bytesWritten = 0
+	counterConn.bytesRead = 0
+
+	result := pgConn.ExecPrepared(ctx,
+		psd.Name,
+		[][]byte{[]byte("1")},
+		nil,
+		[]int16{pgx.BinaryFormatCode, pgx.TextFormatCode, pgx.TextFormatCode, pgx.TextFormatCode, pgx.BinaryFormatCode, pgx.BinaryFormatCode, pgx.BinaryFormatCode, pgx.BinaryFormatCode, pgx.BinaryFormatCode},
+	).Read()
+	require.NoError(t, result.Err)
+	withDescribeBytesWritten := counterConn.bytesWritten
+	withDescribeBytesRead := counterConn.bytesRead
+
+	counterConn.bytesWritten = 0
+	counterConn.bytesRead = 0
+
+	result = pgConn.ExecPreparedStatementDescription(
+		ctx,
+		psd,
+		[][]byte{[]byte("1")},
+		nil,
+		[]int16{pgx.BinaryFormatCode, pgx.TextFormatCode, pgx.TextFormatCode, pgx.TextFormatCode, pgx.BinaryFormatCode, pgx.BinaryFormatCode, pgx.BinaryFormatCode, pgx.BinaryFormatCode, pgx.BinaryFormatCode},
+	).Read()
+	require.NoError(t, result.Err)
+	noDescribeBytesWritten := counterConn.bytesWritten
+	noDescribeBytesRead := counterConn.bytesRead
+
+	assert.Equal(t, 61, withDescribeBytesWritten)
+	assert.Equal(t, 54, noDescribeBytesWritten)
+	assert.Equal(t, 391, withDescribeBytesRead)
+	assert.Equal(t, 153, noDescribeBytesRead)
+
+	ensureConnValid(t, pgConn)
+}
+
 func TestConnExecBatch(t *testing.T) {
 	t.Parallel()