diff --git a/instrumentation/jdbc/library/src/main/java/io/opentelemetry/instrumentation/jdbc/OpenTelemetryDriver.java b/instrumentation/jdbc/library/src/main/java/io/opentelemetry/instrumentation/jdbc/OpenTelemetryDriver.java
index 34a96c2caa0f..8e32d65c9a67 100644
--- a/instrumentation/jdbc/library/src/main/java/io/opentelemetry/instrumentation/jdbc/OpenTelemetryDriver.java
+++ b/instrumentation/jdbc/library/src/main/java/io/opentelemetry/instrumentation/jdbc/OpenTelemetryDriver.java
@@ -253,7 +253,7 @@ public Connection connect(String url, Properties info) throws SQLException {
     Instrumenter<DbRequest, Void> statementInstrumenter =
         JdbcInstrumenterFactory.createStatementInstrumenter(openTelemetry);
 
-    boolean captureQueryParameters = JdbcInstrumenterFactory.captureQueryParameters();
+    boolean captureQueryParameters = JdbcInstrumenterFactory.captureQueryParameters(openTelemetry);
     Instrumenter<DbRequest, Void> transactionInstrumenter =
         JdbcInstrumenterFactory.createTransactionInstrumenter(openTelemetry);
 
diff --git a/instrumentation/jdbc/library/src/main/java/io/opentelemetry/instrumentation/jdbc/internal/JdbcInstrumenterFactory.java b/instrumentation/jdbc/library/src/main/java/io/opentelemetry/instrumentation/jdbc/internal/JdbcInstrumenterFactory.java
index ce9bd75a0bdc..607efe27213e 100644
--- a/instrumentation/jdbc/library/src/main/java/io/opentelemetry/instrumentation/jdbc/internal/JdbcInstrumenterFactory.java
+++ b/instrumentation/jdbc/library/src/main/java/io/opentelemetry/instrumentation/jdbc/internal/JdbcInstrumenterFactory.java
@@ -5,9 +5,12 @@
 
 package io.opentelemetry.instrumentation.jdbc.internal;
 
+import static io.opentelemetry.api.incubator.config.DeclarativeConfigProperties.empty;
 import static java.util.Collections.emptyList;
 
 import io.opentelemetry.api.OpenTelemetry;
+import io.opentelemetry.api.incubator.ExtendedOpenTelemetry;
+import io.opentelemetry.api.incubator.config.DeclarativeConfigProperties;
 import io.opentelemetry.instrumentation.api.incubator.semconv.code.CodeAttributesExtractor;
 import io.opentelemetry.instrumentation.api.incubator.semconv.code.CodeSpanNameExtractor;
 import io.opentelemetry.instrumentation.api.incubator.semconv.db.DbClientMetrics;
@@ -32,14 +35,30 @@ public final class JdbcInstrumenterFactory {
   private static final JdbcNetworkAttributesGetter netAttributesGetter =
       new JdbcNetworkAttributesGetter();
 
-  public static boolean captureQueryParameters() {
-    return ConfigPropertiesUtil.getBoolean(
-        "otel.instrumentation.jdbc.experimental.capture-query-parameters", false);
+  public static boolean captureQueryParameters(OpenTelemetry openTelemetry) {
+    if (openTelemetry instanceof ExtendedOpenTelemetry) {
+      ExtendedOpenTelemetry extendedOpenTelemetry = (ExtendedOpenTelemetry) openTelemetry;
+
+      DeclarativeConfigProperties instrumentationConfig =
+          extendedOpenTelemetry.getConfigProvider().getInstrumentationConfig();
+
+      if (instrumentationConfig == null) {
+        return false;
+      }
+
+      return instrumentationConfig
+          .getStructured("jdbc", empty())
+          .getStructured("experimental", empty())
+          .getBoolean("capture-query-parameters", false);
+    } else {
+      return ConfigPropertiesUtil.getBoolean(
+          "otel.instrumentation.jdbc.experimental.capture-query-parameters", false);
+    }
   }
 
   public static Instrumenter<DbRequest, Void> createStatementInstrumenter(
       OpenTelemetry openTelemetry) {
-    return createStatementInstrumenter(openTelemetry, captureQueryParameters());
+    return createStatementInstrumenter(openTelemetry, captureQueryParameters(openTelemetry));
   }
 
   static Instrumenter<DbRequest, Void> createStatementInstrumenter(
@@ -48,8 +67,7 @@ static Instrumenter<DbRequest, Void> createStatementInstrumenter(
         openTelemetry,
         emptyList(),
         true,
-        ConfigPropertiesUtil.getBoolean(
-            "otel.instrumentation.common.db-statement-sanitizer.enabled", true),
+        statementSanitizationEnabled(openTelemetry, true),
         captureQueryParameters);
   }
 
@@ -97,10 +115,8 @@ public static Instrumenter<DataSource, DbInfo> createDataSourceInstrumenter(
 
   public static Instrumenter<DbRequest, Void> createTransactionInstrumenter(
       OpenTelemetry openTelemetry) {
-    return createTransactionInstrumenter(
-        openTelemetry,
-        ConfigPropertiesUtil.getBoolean(
-            "otel.instrumentation.jdbc.experimental.transaction.enabled", false));
+
+    return createTransactionInstrumenter(openTelemetry, transactionEnabled(openTelemetry, false));
   }
 
   public static Instrumenter<DbRequest, Void> createTransactionInstrumenter(
@@ -122,5 +138,49 @@ public static Instrumenter<DbRequest, Void> createTransactionInstrumenter(
         .buildInstrumenter(SpanKindExtractor.alwaysClient());
   }
 
+  private static boolean transactionEnabled(OpenTelemetry openTelemetry, boolean defaultEnabled) {
+    if (openTelemetry instanceof ExtendedOpenTelemetry) {
+      ExtendedOpenTelemetry extendedOpenTelemetry = (ExtendedOpenTelemetry) openTelemetry;
+
+      DeclarativeConfigProperties instrumentationConfig =
+          extendedOpenTelemetry.getConfigProvider().getInstrumentationConfig();
+
+      if (instrumentationConfig == null) {
+        return defaultEnabled;
+      }
+
+      return instrumentationConfig
+          .getStructured("jdbc", empty())
+          .getStructured("experimental", empty())
+          .getStructured("transaction", empty())
+          .getBoolean("enabled", defaultEnabled);
+    } else {
+      return ConfigPropertiesUtil.getBoolean(
+          "otel.instrumentation.jdbc.experimental.transaction.enabled", defaultEnabled);
+    }
+  }
+
+  private static boolean statementSanitizationEnabled(
+      OpenTelemetry openTelemetry, boolean defaultEnabled) {
+    if (openTelemetry instanceof ExtendedOpenTelemetry) {
+      ExtendedOpenTelemetry extendedOpenTelemetry = (ExtendedOpenTelemetry) openTelemetry;
+
+      DeclarativeConfigProperties instrumentationConfig =
+          extendedOpenTelemetry.getConfigProvider().getInstrumentationConfig();
+
+      if (instrumentationConfig == null) {
+        return defaultEnabled;
+      }
+
+      return instrumentationConfig
+          .getStructured("common", empty())
+          .getStructured("db-statement-sanitizer", empty())
+          .getBoolean("enabled", defaultEnabled);
+    } else {
+      return ConfigPropertiesUtil.getBoolean(
+          "otel.instrumentation.common.db-statement-sanitizer.enabled", defaultEnabled);
+    }
+  }
+
   private JdbcInstrumenterFactory() {}
 }