The load_picklist method of sourmash_args requires the entire args namespace instead of filename:colname:coltype:picklistStyle. The need for an args object makes it difficult to code in simple scripts or nested functions. Namely, the ones used in sourmash plugins like https://github.com/dib-lab/sourmash_plugin_pangenomics/blob/main/src/sourmash_plugin_pangenomics.py
See L34 of a simple picklist script I wrote.